Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17670219 | 1.00 | EGFR (0.38) | EGFRERBB2CCNA2CDK2TTK | |
| SCHEMBL31030279 | 0.89 | EGFR (0.37) | EGFRERBB2KDRSYKLMNA | |
| SCHEMBL17670296 | 0.89 | EGFR (0.37) | EGFRERBB2KDRSYKLMNA | |
| SCHEMBL17670190 | 0.88 | EGFR (0.39) | EGFRERBB2SYKALKLMNA | |
| SCHEMBL17670196 | 0.88 | EGFR (0.39) | EGFRERBB2ALKLMNAKMT2A | |
| SCHEMBL30384575 | 0.88 | EGFR (0.39) | EGFRERBB2ALKLMNAKMT2A | |
| SCHEMBL17670228 | 0.87 | EGFR (0.46) | EGFRERBB2TTKALDH1A1 | |
| SCHEMBL17670292 | 0.86 | EGFR (0.36) | EGFRERBB2KDRALKLMNA | |
| SCHEMBL17670104 | 0.85 | EGFR (0.38) | EGFRERBB2CCNA2CDK2TTK | |
| SCHEMBL17670396 | 0.85 | EGFR (0.43) | EGFRERBB2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725554-A2 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR MUTANT KINASE ACTIVITIES | Yuhan Corporation (KR) | 2026-04-15 | — | — | EP | disclosed |