SCHEMBL34464710

SCHEMBL34464710

CCOC(=O)/C=C/C1COC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.42
MAPT P10636 2/20 0.40
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TTR P02766 1/20 0.35
DPP4 P27487 1/20 0.35
ATM Q13315 1/20 0.34
TSHR P16473 1/20 0.34
PPM1B O75688 1/20 0.34
PTPN1 P18031 1/20 0.34
PPP1CC P36873 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17075138 1.00 HCAR2 (0.47) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL101275 0.86 HCAR2 (0.42) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL18269649 0.84 HCAR2 (0.40) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL18027847 0.84 HCAR2 (0.40) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL7512241 0.82 HCAR2 (0.52) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL18828565 0.82 HCAR2 (0.52) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL7512242 0.82 HCAR2 (0.52) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL2292877 0.82 HCAR2 (0.44) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL2292881 0.82 HCAR2 (0.44) HCAR2L3MBTL1MAPTTDP1CA12
SCHEMBL1126534 0.79 HCAR2 (0.48) HCAR2L3MBTL1MAPTTDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS HCAR2 4524/4885L3MBTL1 1458/4885MAPT 3017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.