Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184901 | 0.75 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL7180580 | 0.68 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL7185920 | 0.67 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL28616966 | 0.66 | TSHR (0.35) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1041783 | 0.65 | TSHR (0.48) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL15825971 | 0.64 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL5271167 | 0.63 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL16291088 | 0.63 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1408575 | 0.63 | — | — | |
| SCHEMBL28125584 | 0.63 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816464-B2 | Polymer particle dispersion, cosmetic composition comprising it and cosmetic process using it | L'OREAL, S.A. (FR) | 2010-10-19 | — | — | US | claimed |