SCHEMBL34469370

SCHEMBL34469370

CC(=O)N1CCc2c(c(N(C)c3ccc(-n4cc([C@H]5CCNC5)c5cc(C)nnc54)c(C(F)F)c3)nn2C2CCOCC2)C1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 20/20 0.43
▸ BRD4 O60885 9/20 0.41
▸ EP300 Q09472 2/20 0.41
▸ CECR2 Q9BXF3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34469381 1.00 CREBBP (0.43) CREBBPBRD4EP300CECR2
SCHEMBL34469405 1.00 CREBBP (0.43) CREBBPBRD4EP300CECR2
SCHEMBL34469367 0.86 CREBBP (0.41) CREBBPBRD4EP300CECR2
SCHEMBL34469371 0.85 CREBBP (0.49) CREBBPBRD4EP300CECR2
SCHEMBL34469825 0.81 CREBBP (0.42) CREBBPBRD4EP300CECR2
SCHEMBL31208162 0.77 CREBBP (0.49) CREBBPBRD4EP300CECR2
SCHEMBL31208166 0.77 CREBBP (0.49) CREBBPBRD4
SCHEMBL34471816 0.77 CREBBP (0.53) CREBBPBRD4
SCHEMBL31153457 0.64 CREBBP (0.33) CREBBPBRD4
SCHEMBL17794481 0.63 CREBBP (0.73) CREBBPBRD4EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090330-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 — — WO disclosed
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