Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 17/20 | 0.61 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.48 |
| ▸ | ELOC | Q15369 | 3/20 | 0.41 |
| ▸ | ELOB | Q15370 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21456410 | 0.94 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL23205572 | 0.94 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL21456393 | 0.92 | VHL (0.64) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL30312575 | 0.92 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL21456404 | 0.92 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL23205395 | 0.92 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL23205598 | 0.91 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL23205220 | 0.91 | VHL (0.59) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL23205266 | 0.91 | VHL (0.60) | VHLSMARCA2SMARCA4ELOCELOB | |
| SCHEMBL21673932 | 0.90 | VHL (0.55) | VHLSMARCA2SMARCA4SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090411-A1 | BRM AND BRG1 TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS INCORPORATED (US) | 2026-04-30 | — | — | WO | disclosed |