SCHEMBL34470944

SCHEMBL34470944

CNC(=O)N1CCc2c(c(N(C)c3cc(OC4COC4)c(Cl)cn3)nn2C2CCOCC2)C1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 20/20 0.47
▸ BRD4 O60885 8/20 0.45
▸ EP300 Q09472 2/20 0.42
▸ BRPF1 P55201 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34471865 0.80 CNR2 (0.31) —
SCHEMBL34471831 0.79 CREBBP (0.49) CREBBPBRD4EP300BRPF1
SCHEMBL34471340 0.74 CREBBP (0.49) CREBBPBRD4EP300
SCHEMBL34471850 0.72 PDE4D (0.35) CREBBPBRD4
SCHEMBL34470836 0.72 CREBBP (0.37) CREBBPBRD4
SCHEMBL34471188 0.72 CREBBP (0.37) CREBBPBRD4
SCHEMBL34470797 0.72 CREBBP (0.43) CREBBPBRD4EP300
SCHEMBL34470779 0.71 CREBBP (0.40) CREBBPBRD4EP300
SCHEMBL34470772 0.70 CREBBP (0.42) CREBBPBRD4
SCHEMBL34471816 0.68 CREBBP (0.53) CREBBPBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090317-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 — — WO disclosed
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