SCHEMBL3447108

SCHEMBL3447108

C=CCCCCCCCCCCCC/C(=C/C)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
MAPT P10636 3/20 0.48
ABCC4 O15439 1/20 0.48
ALDH1A1 P00352 3/20 0.47
LMNA P02545 3/20 0.47
LPAR3 Q9UBY5 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34
USP2 O75604 2/20 0.34
RECQL P46063 2/20 0.34
CYP3A4 P08684 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FAAH O00519 1/20 0.32
TRPA1 O75762 1/20 0.32
GMNN O75496 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
APEX1 P27695 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3447168 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL846699 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL9174406 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL9174407 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL846700 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL2066527 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL2066529 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL3447165 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL3447109 1.00 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL848257 0.98 TSHR (0.46) TSHRMAPTABCC4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816003-B1 Adhesive film composition Arrowhead Coating and Converting, Inc. (US) 2010-10-19 US disclosed
EP-0331312-B1 PROCESS FOR PREPARING ELASTOMERIC POLYARYLATE GRAFT COPOLYMERS AND POLYARYLATE BEARING ONE DIHYDROCYCLOBUTENE END GROUP AMOCO CORPORATION (US) 1992-11-11 EP disclosed
US-4937287-A Addition-condensation copolymers; oxidation and heat resistance, photostability AMOCO CORPORATION (US) 1990-06-26 US disclosed
EP-0331312-A1 Process for preparing elastomeric polyarylate graft copolymers and polyarylate bearing one dihydrocyclobutene end group AMOCO CORPORATION (US) 1989-09-06 EP disclosed
US-4303697-A Process for improving the adhesion of paint to polyolefin surfaces E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-01 US disclosed
US-4021600-A Slurry polymerization process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-03 US disclosed