SCHEMBL34475640

SCHEMBL34475640

COc1ccc(Cn2c(=O)oc3cc(C=O)ccc32)cc1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.52
▸ MIF P14174 5/20 0.50
▸ CD74 P04233 3/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ TNIK Q9UKE5 3/20 0.48
▸ NPC1 O15118 1/20 0.47
▸ PTGER4 P35408 1/20 0.47
▸ TP53 P04637 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667438 0.84 MIF (0.71) POLBMIFCD74MEN1KMT2A
SCHEMBL18805706 0.82 MIF (0.62) POLBMIFCD74MEN1KMT2A
SCHEMBL31667732 0.82 POLB (0.54) POLBMIFCD74MEN1KMT2A
SCHEMBL32683548 0.81 MIF (0.47) MIFKMT2ATNIKNPC1TP53
SCHEMBL32674487 0.79 MIF (0.58) POLBMIFCD74MEN1KMT2A
SCHEMBL243322 0.78 MIF (0.73) POLBMIFCD74MEN1KMT2A
SCHEMBL20725151 0.76 MIF (0.76) POLBMIFCD74MEN1KMT2A
SCHEMBL31700596 0.76 MEN1 (0.38) POLBMEN1KMT2APTGER4ALDH1A1
SCHEMBL32674482 0.75 MIF (0.51) POLBMIFCD74KMT2ATP53
SCHEMBL18805695 0.75 IDO1 (0.72) POLBMIFCD74KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026088071-A1 SUBSTITUTED FUSED HETEROARYL LACTAM COMPOUNDS PFIZER INC. (US) 2026-04-30 — — WO disclosed
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