SCHEMBL3449196

SCHEMBL3449196

Nc1ccn([C@H]2C[C@H](O)[C@@H](C(O)I)O2)c(=O)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
LMNA P02545 3/20 0.49
PDE3A Q14432 3/20 0.49
CACNA1F O60840 2/20 0.49
ALB P02768 2/20 0.49
MAPT P10636 2/20 0.49
CACNA1D Q01668 2/20 0.49
CACNA1S Q13698 2/20 0.49
CACNA1C Q13936 2/20 0.49
THRB P10828 1/20 0.45
MTOR P42345 1/20 0.45
MDM2 Q00987 1/20 0.45
NCOA1 Q15788 1/20 0.45
NCOA3 Q9Y6Q9 1/20 0.45
NT5E P21589 1/20 0.45
POLG P54098 2/20 0.44
PDE4D Q08499 1/20 0.43
SLC29A1 Q99808 1/20 0.43
P2RY2 P41231 3/20 0.42
P2RY4 P51582 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5666376 0.92 POLB (0.53) POLBLMNAPDE3ACACNA1FALB
SCHEMBL28799641 0.92 POLB (0.53) POLBLMNAPDE3ACACNA1FALB
SCHEMBL7794947 0.90 POLB (0.51) POLBLMNAPDE3ACACNA1FALB
SCHEMBL51649 0.89 POLB (0.50) POLBLMNAPDE3ACACNA1FALB
SCHEMBL127179 0.89 POLB (0.50) POLBLMNAPDE3ACACNA1FALB
SCHEMBL3178721 0.89 POLB (0.50) POLBLMNAPDE3ACACNA1FALB
SCHEMBL13471863 0.89 POLB (0.50) POLBLMNAPDE3ACACNA1FALB
SCHEMBL4199985 0.89 POLB (0.50) POLBLMNAPDE3ACACNA1FALB
SCHEMBL4201132 0.89 POLB (0.50) POLBLMNAPDE3ACACNA1FALB
SCHEMBL3896397 0.87 POLB (0.48) POLBLMNAPDE3ACACNA1FALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115315430-A Nucleic acid synthesis method using segmented phosphoramidite compound 日东电工株式会社 2022-11-08 CN disclosed
US-7767449-B1 Methods using modified vaccinia virus HEALTH RESEARCH INCORPORATED (US) 2010-08-03 US disclosed
EP-1435826-A4 DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF UNIV TULANE (US) 2009-07-15 EP disclosed
WO-2008085611-A2 DESIGNER THERAPHY OF PANCREATIC TUMORS UNIVERSITY OF MIAMI (US) 2008-07-17 WO disclosed
US-20060160125-A1 Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms UNIVERSITY OF ROCHESTER (US) 2006-07-20 US disclosed
US-7033753-B1 Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms UNIVERSITY OF ROCHESTER (US) 2006-04-25 US disclosed
EP-1435826-A2 DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF The Administrators of The Tulane Educational Fund (US) 2004-07-14 EP disclosed
US-6677311-B1 DNA EXPRESSING AN EXOGENOUS HERPES SIMPLEX THYMIDINE KINASE ENZYME SELECTIVELY CONVERTS LATENT TOXIN INTO CELL TOXIN TO INHIBIT GROWTH OR CAUSE DEATH OF A TISSUE-TYPE OR CELL LINE THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2004-01-13 US disclosed
WO-2003028527-A2 DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2003-04-10 WO disclosed
EP-0149040-B2 Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same NOVAGENE INC (US) 2002-05-22 EP disclosed
US-4609548-A NON-PRODUCERS OF THYMIDINE KINASE; VETERINARY MEDICINE NOVAGENE, LTD. (US) 1986-09-02 US disclosed
US-4603112-A Modified vaccinia virus HEALTH RESEARCH, INCORPORATED (US) 1986-07-29 US disclosed
US-4579821-A FUSION OF DNA PROMOTHER/REGULATOR WITH GENES UNIVERSITY PATENTS, INC. (US) 1986-04-01 US disclosed
EP-0094428-A4 CONTROL OF DNA SEQUENCE TRANSCRIPTION. UNIVERSITY PATENTS INC (US) 1986-01-07 EP disclosed
EP-0149040-A2 Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same NOVAGENE, INC. (US) 1985-07-24 EP disclosed
US-4514497-A DO NOT PRODUCE THYMIDINE KINASE- TEMPERATURE RESISTANCE NOVAGENE, LTD. (US) 1985-04-30 US disclosed
US-4465769-A Non-transformed thymidine kinaseless cell line and its use for testing tumorigenic potential of genes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1984-08-14 US disclosed
EP-0094428-A1 CONTROL OF DNA SEQUENCE TRANSCRIPTION. UNIVERSITY PATENTS INC (US) 1983-11-23 EP disclosed
EP-0083286-A2 Modified vaccinia virus and methods for making and using the same HEALTH RESEARCH, INCORPORATED (US) 1983-07-06 EP disclosed
WO-1983001783-A1 CONTROL OF DNA SEQUENCE TRANSCRIPTION UNIVERSITY PATENTS INC (US) 1983-05-26 WO disclosed