Trolamine

Trolamine

SCHEMBL3453642

OB(O)Oc1cccc2ccc3cc4ccccc4cc3c12.OCCN(CCO)CCO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ERBB2 P04626 1/20 0.33
CYP1A2 P05177 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTR1B P28222 1/20 0.31
GAA P10253 1/20 0.31
RXRA P19793 1/20 0.30
PPARG P37231 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2374259 0.89 HTR1B (0.38) ALDH1A1KMT2ATSHRHSD17B10HTR1B
SCHEMBL19259375 0.88 CYP1A2 (0.41) KDM4EALDH1A1MEN1KMT2AERBB2
SCHEMBL911197 0.86 HTR1B (0.47) MEN1KMT2AHTR1B
Phosphine SCHEMBL3288817 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2
SCHEMBL19252585 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2
SCHEMBL445634 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2
Hydrogen Sulfide SCHEMBL17372873 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2
SCHEMBL1314570 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2
SCHEMBL911163 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2
Ammonia Solution, Strong SCHEMBL1035827 0.86 CYP1A2 (0.40) KDM4EALDH1A1MEN1KMT2AERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1454921-B1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE TOKUYAMA CORP (JP) 2021-07-28 EP disclosed
EP-2213275-B1 CURABLE COMPOSITION FOR DENTAL APPLICATIONS TOKUYAMA DENTAL CORP (JP) 2019-04-10 EP disclosed
US-8765837-B2 Dental curable composition TOKUYAMA DENTAL CORPORATION (JP) 2014-07-01 US disclosed
US-20100261144-A1 Dental Curable Composition TOKUYAMA DENTAL CORPORATION (JP) 2010-10-14 US disclosed
EP-2213275-A1 CURABLE COMPOSITION FOR DENTAL APPLICATIONS Tokuyama Dental Corporation (JP) 2010-08-04 EP disclosed
US-20050009946-A1 Radical polymerization catalyst and adhesive kit for dental use TOKUYAMA CORPORATION (JP) 2005-01-13 US disclosed
EP-1454921-A1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE Tokuyama Corporation (JP) 2004-09-08 EP disclosed