⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049633 | 0.81 | — | — | |
| SCHEMBL2560372 | 0.81 | — | — | |
| SCHEMBL25379957 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL4572764 | 0.78 | — | — | |
| SCHEMBL325804 | 0.75 | TSHR (0.40) | — | |
| SCHEMBL16944229 | 0.74 | — | — | |
| SCHEMBL26277652 | 0.74 | — | — | |
| SCHEMBL4557044 | 0.73 | — | — | |
| SCHEMBL518870 | 0.73 | — | — | |
| SCHEMBL10204097 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536717-B1 | AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-04 | — | — | EP | disclosed |
| WO-2009039442-A9 | NFIA IN GLIAL FATE DETERMINATION, GLIOMA THERAPY AND ASTROCYTOMA TREATMENT | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2009039442-A1 | NFIA IN GLIAL FATE DETERMINATION, GLIOMA THERAPY AND ASTROCYTOMA TREATMENT | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-03-26 | — | — | WO | disclosed |