SCHEMBL3454672

SCHEMBL3454672

Cc1nc(-c2c(OCCC3CC3)cc[nH]c2=O)sc1C(=O)NCc1cccnc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 16/20 0.53
CHRM4 P08173 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478653 0.91 SCD (0.59) SCDCHRM4
SCHEMBL3454545 0.87 SCD (0.49) SCD
SCHEMBL3454462 0.86 SCD (0.51) SCDCHRM4
SCHEMBL3454191 0.86 RECQL (0.51) SCDCHRM4
SCHEMBL3454978 0.85 SCD (0.50) SCD
SCHEMBL3455523 0.84 SCD (0.54) SCD
SCHEMBL3454095 0.83 SCD (0.50) SCD
SCHEMBL3455045 0.81 SCD (0.57) SCD
SCHEMBL3454091 0.81 SCD (0.40) SCD
SCHEMBL3455692 0.81 SCD (0.52) SCDCHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007143597-A9 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-11-11 WO claimed