SCHEMBL3454886

SCHEMBL3454886

Cc1nc(-c2c(OCc3ccc(Cl)nc3)cc[nH]c2=O)sc1C(=O)NCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCD O00767 14/20 0.49
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3455858 0.91 SCD (0.54) SCD
SCHEMBL3454978 0.89 SCD (0.50) SCD
SCHEMBL3455023 0.88 SCD (0.51) SCDPPARDPPARAL3MBTL1
SCHEMBL3456448 0.88 SCD (0.51) SCDPPARDPPARAL3MBTL1
SCHEMBL3454894 0.86 SCD (0.49) SCDPPARDPPARA
SCHEMBL3454226 0.85 PPARA (0.53) SCDPPARDPPARA
SCHEMBL3454462 0.85 SCD (0.51) SCD
SCHEMBL3454214 0.84 SCD (0.49) SCD
SCHEMBL3454273 0.84 SCD (0.50) SCDPPARDPPARA
SCHEMBL3454229 0.84 SCD (0.55) SCDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007143597-A9 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-11-11 WO claimed