Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424089 | 0.89 | GCK (0.47) | GCKKCNH2ABL1BCR | |
| SCHEMBL15016330 | 0.89 | GCK (0.47) | GCKKCNH2ABL1BCR | |
| SCHEMBL425302 | 0.87 | GCK (0.45) | GCKKCNH2ABL1BCR | |
| SCHEMBL420638 | 0.82 | GCK (0.42) | GCKKCNH2ABL1BCR | |
| SCHEMBL423799 | 0.81 | GCK (0.48) | GCKKCNH2ABL1BCR | |
| SCHEMBL424190 | 0.80 | GCK (0.42) | GCKKCNH2ABL1BCR | |
| SCHEMBL15016319 | 0.80 | GCK (0.47) | GCKKCNH2ABL1BCR | |
| SCHEMBL422961 | 0.80 | GCK (0.47) | GCKKCNH2ABL1BCR | |
| SCHEMBL424513 | 0.77 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL426227 | 0.77 | GCK (0.47) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239253-A1 | NOVEL PHENYLPYRROLE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-10-13 | — | — | EP | disclosed |