SCHEMBL3456367

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3456321	1.00	S1PR1 (0.49)	S1PR1NPC1RAB9ANFKB1NFKB2
	SCHEMBL3456527	0.91	S1PR1 (0.51)	S1PR1NPC1RAB9AS1PR4S1PR5
	SCHEMBL3456549	0.91	S1PR1 (0.51)	S1PR1NPC1RAB9AS1PR4S1PR5
	SCHEMBL3456341	0.89	S1PR1 (0.57)	S1PR1S1PR4S1PR5S1PR3MAP4K4
	SCHEMBL3456339	0.89	S1PR1 (0.57)	S1PR1S1PR4S1PR5S1PR3MAP4K4
	SCHEMBL3456347	0.89	S1PR1 (0.46)	S1PR1NPC1RAB9AS1PR4S1PR5
	SCHEMBL3456348	0.89	S1PR1 (0.46)	S1PR1NPC1RAB9AS1PR4S1PR5
	SCHEMBL3456954	0.89	S1PR1 (0.58)	S1PR1NPC1RAB9ANFKB1NFKB2
	SCHEMBL3456955	0.89	S1PR1 (0.58)	S1PR1NPC1RAB9ANFKB1NFKB2
	SCHEMBL3098732	0.89	S1PR1 (0.65)	S1PR1S1PR4S1PR5S1PR3DYRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.