Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423926 | 0.93 | GCK (0.44) | GCKKCNH2 | |
| SCHEMBL423254 | 0.92 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL422623 | 0.90 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL13127997 | 0.90 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL424788 | 0.90 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL424978 | 0.89 | GCK (0.40) | GCKKCNH2 | |
| SCHEMBL424379 | 0.88 | GCK (0.39) | GCKKCNH2 | |
| SCHEMBL423046 | 0.85 | GCK (0.42) | GCKKCNH2 | |
| SCHEMBL423927 | 0.83 | GCK (0.41) | GCKKCNH2RARG | |
| SCHEMBL425663 | 0.83 | GCK (0.41) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239253-B1 | NOVEL PHENYLPYRROLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| US-8415359-B2 | Phenylpyrrole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-04-09 | — | — | US | disclosed |
| EP-2239253-A1 | NOVEL PHENYLPYRROLE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-10-13 | — | — | EP | disclosed |