Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464001 | 0.84 | MAOB (0.49) | MAOBFFAR1FFAR4 | |
| SCHEMBL28624803 | 0.82 | MAOB (0.61) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| SCHEMBL10452980 | 0.82 | MAOB (0.65) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| SCHEMBL8264422 | 0.81 | MAOB (0.64) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| SCHEMBL10865258 | 0.80 | MAOB (0.68) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| SCHEMBL963783 | 0.80 | MAOB (0.59) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| Hydrochloric Acid SCHEMBL23235866 | 0.80 | MAOB (0.62) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| SCHEMBL4229059 | 0.79 | MAOB (0.71) | MAOB | |
| SCHEMBL21340421 | 0.79 | MAOB (0.61) | MAOBS1PR1S1PR5KMT2AFFAR1 | |
| SCHEMBL11860320 | 0.79 | MAOB (0.61) | MAOBS1PR1S1PR5KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |