SCHEMBL345819

SCHEMBL345819

[CH]C#C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3030006 0.63
SCHEMBL2825402 0.60
SCHEMBL18583040 0.60
SCHEMBL7714929 0.55
SCHEMBL7617769 0.55
SCHEMBL23721699 0.55
SCHEMBL5133363 0.55
SCHEMBL3818637 0.55
SCHEMBL4330924 0.55
SCHEMBL1418382 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024120442-A1 PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) 2024-06-13 WO claimed
EP-3919496-A1 POLYCYCLIC COMPOUND INHIBITING MNK1 AND MNK2 Novostar Pharmaceuticals, Ltd. (CN) 2021-12-08 EP claimed
EP-1480944-B1 SUBSTITUTED ARYL KETONES BAYER IP GMBH (DE) 2016-08-10 EP claimed
US-7807703-B2 Herbicides; pesticides BAYER CROPSCIENCE AG (DE) 2010-10-05 US claimed
US-20050153958-A1 SUBSTITUTED ARYL KETONES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2005-07-14 US claimed
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US claimed
US-5633253-A TREATMENT OF DISEASES OF RHEUMATOID GENESIS CIBY-GEIGY CORPORATION (US) 1997-05-27 US claimed
EP-0211598-B1 Pesticidal compounds WELLCOME FOUND (GB) 1993-12-15 EP claimed
CN-118339156-A 2-Diazo-3-oxo-2, 3-dihydrospiro [ indene-1, 9' -xanthene ] derivatives and similar compounds as photoactive fluorescent compounds for protein labelling 爱康治疗公司 2024-07-12 CN disclosed
US-20240199553-A1 DIFLUOROMETHYLATION REACTION OF HETEROCYCLIC RING USING TETRAFLUOROETHYLENE AGC Inc. (JP) 2024-06-20 US disclosed
US-20240197888-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2024-06-20 US disclosed
EP-4385977-A1 DIFLUOROMETHYLATION REACTION OF HETEROCYCLIC RING USING TETRAFLUOROETHYLENE AGC INC. (JP) 2024-06-19 EP disclosed
WO-2024120466-A1 MONOSACCARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS SURIO THERAPEUTICS CO., LTD (CN) 2024-06-13 WO disclosed
WO-2024120442-A1 PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) 2024-06-13 WO disclosed
EP-0332387-B1 Triazole derivatives, their preparation and their use as fungicides SANKYO CO (JP) 1993-11-24 EP disclosed
EP-0507863-A4 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF 1993-07-07 EP disclosed
US-5211737-A Herbicides and safeners BASF AKTIENGESELLSCHAFT (DE) 1993-05-18 US disclosed
EP-0507863-A1 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1992-10-14 EP disclosed
US-4999352-A Antidepressants or fungicides HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed
EP-0332387-A1 Triazole derivatives, their preparation and their use as fungicides Sankyo Company Limited (JP) 1989-09-13 EP disclosed