SCHEMBL3458197

SCHEMBL3458197

COCCc1n(C)cc[n+]1C

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 2/20 0.45
APOBEC3G Q9HC16 2/20 0.45
KDM4E B2RXH2 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTT P42858 1/20 0.44
HDAC8 Q9BY41 4/20 0.43
POLB P06746 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16673992 0.85 HDAC8 (0.52) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL5944565 0.83 HDAC8 (0.39) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL3458293 0.82 APOBEC3A (0.54) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL16673901 0.81 HDAC8 (0.48) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL16674097 0.81 HDAC8 (0.48) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL3457315 0.79 SMN1; SMN2 (0.35) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL372970 0.79 HDAC8 (0.46) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
Fluoride Ion SCHEMBL1898517 0.78 HDAC8 (0.45) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL1829114 0.78 APOBEC3A (0.46) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2HTT
SCHEMBL3457313 0.77 CTDSP1 (0.31) APOBEC3AAPOBEC3GKDM4ESMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100321863-A1 ACTIVATED CARBON AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-23 US disclosed
US-7785495-B2 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-31 US disclosed
EP-2093191-A1 ACTIVATED CARBON AND METHOD FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-08-26 EP disclosed
US-20090103241-A1 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 US disclosed
EP-1905740-A1 ELECTRIC DOUBLE LAYER CAPACITOR Sumitomo Chemical Company, Limited (JP) 2008-04-02 EP disclosed
US-20060186419-A1 Light-emitting device KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090103241-A1 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 CBR1, CYP24A1, CALU APOBEC3A 3809/4885APOBEC3G 4252/4885KDM4E 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.