SCHEMBL3459

SCHEMBL3459

Brc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29127345 0.97
SCHEMBL8796316 0.97
SCHEMBL3860691 0.73
SCHEMBL2922010 0.69
SCHEMBL8961761 0.67 MAPT (0.31)
SCHEMBL115447 0.67 CYP3A4 (0.33)
SCHEMBL10458472 0.66 HDAC8 (0.30)
SCHEMBL1042104 0.65
SCHEMBL185933 0.65
SCHEMBL4433093 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 29272 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239755-A1 SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-07-18 US claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118344293-A Acenaphthene dimer derivative, and preparation method and application thereof 中国石油化工股份有限公司 2024-07-16 CN claimed
CN-118344336-A 2-Alkylene-5-aminothiophene-3-ketone compound and preparation method and application thereof 浙江师范大学 2024-07-16 CN claimed
CN-118344291-A Method for preparing imide by rearrangement of isoamide and application thereof 中国石油化工股份有限公司 2024-07-16 CN claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-118344292-A Acenaphthene derivative and preparation method thereof, acenaphthene derivative material and preparation method and application thereof 中国石油化工股份有限公司 2024-07-16 CN claimed
CN-114369011-B New green method for preparing 2-diaryl methyl substituted-1-naphthol compound 湖南理工学院 2024-07-09 CN claimed
CN-117143099-B Evodiamine derivative, preparation method thereof and application of evodiamine derivative as PGAM1 inhibitor 陕西中医药大学 2024-07-09 CN claimed
CN-118290406-A Method for synthesizing tetrahydrofuran compound by organic catalysis 中国海洋大学 2024-07-05 CN claimed
US-3952002-A FUNGICIDE, MICROBIOCIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed
US-3951592-A Polyester fabric materials dyed with monoazo dyes made from 4-amino-7-nitrobenzotriazole AMERICAN COLOR & CHEMICAL CORPORATION (US) 1976-04-20 US claimed
US-3948938-A Polymeric materials colored with yellow methine dyes and pigments AMERICAN COLOR & CHEMICAL CORPORATION (US) 1976-04-06 US claimed
US-3948893-A COCCIDIOSIS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US claimed
US-3947470-A CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS SMITHKLINE CORPORATION (US) 1976-03-30 US claimed
US-3944389-A Detection of chloromethyl methyl ether or bis-chloro-methyl ether THE DOW CHEMICAL COMPANY (US) 1976-03-16 US claimed
US-3936442-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3931356-A POLYMERIZATION MONSANTO COMPANY (US) 1976-01-06 US claimed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed
US-3931336-A Production of oxyalkylated α-hydroxy acetylenic compounds BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed