Zinc Ion

Zinc Ion

SCHEMBL345932

CCCCCCCCCCCCCCOP(=S)([S-])OCCCCCCCCCCCCCC.CCCCCCCCCCCCCCOP(=S)([S-])OCCCCCCCCCCCCCC.[Zn+2]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 15/20 0.59
LPAR2 Q9HBW0 13/20 0.59
LPAR1 Q92633 10/20 0.48
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
LPAR6 P43657 5/20 0.41
LPAR4 Q99677 5/20 0.41
LPAR5 Q9H1C0 5/20 0.41
CYP3A4 P08684 1/20 0.39
LMNA P02545 1/20 0.39
ESR1 P03372 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
CDC25A P30304 1/20 0.39
AGTR1 P30556 1/20 0.39
AKT1 P31749 1/20 0.39
ADRA1A P35348 1/20 0.39
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL346365 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL163988 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL164628 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL345959 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL164653 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL346116 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL346739 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL164250 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL163340 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CA12CA1
Zinc Ion SCHEMBL1682497 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1612258-B1 Use of additives in a lubricant composition for automotive driving system TONENGENERAL SEKIYU KK (JP) 2018-11-21 EP disclosed
US-20120012076-A1 METHOD OF OPERATING A HYBRID ENGINE CASTROL LIMITED (GB) 2012-01-19 US disclosed
WO-2010046620-A1 METHOD OF OPERATING A HYBRID ENGINE CASTROL LIMITED (GB) 2010-04-29 WO disclosed
EP-2177596-A1 Method of operating a hybrid engine Castrol Limited (GB) 2010-04-21 EP disclosed
US-7399736-B2 Low viscosity, high abrasion resistance engine oil composition TONENGENERAL SEKIYU K.K. (JP) 2008-07-15 US disclosed
EP-1612258-A2 Lubricant composition for automotive driving system TonenGeneral Sekiyu Kabushiki Kaisha (JP) 2006-01-04 EP disclosed
US-20050267002-A1 Lubricant composition for automobile driving system KATO TOMOHIRO 2005-12-01 US disclosed
EP-1600495-A1 A low viscosity, high abrasion resistance engine oil composition TonenGeneral Sekiyu Kabushiki Kaisha (JP) 2005-11-30 EP disclosed
US-20050221998-A1 Low viscosity, high abrasion resistance engine oil composition MARUMO MIYOSHI 2005-10-06 US disclosed