Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.58 |
| ▸ | TERT | O14746 | 4/20 | 0.44 |
| ▸ | CYCS | P99999 | 3/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460026 | 1.00 | TOP1 (0.58) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL15188824 | 1.00 | TOP1 (0.58) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL8182077 | 0.93 | TOP1 (0.47) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL13183880 | 0.93 | TOP1 (0.51) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL31315103 | 0.85 | TOP1 (0.76) | TOP1TERTCYCSENPP2ABCG2 | |
| SCHEMBL3459764 | 0.84 | TOP1 (0.70) | TOP1TERTCYCSENPP2ABCG2 | |
| SCHEMBL245937 | 0.83 | TOP1 (0.78) | TOP1TERTCYCSENPP2ABCG2 | |
| SCHEMBL29961137 | 0.83 | TOP1 (0.78) | TOP1TERTCYCSENPP2ABCG2 | |
| SCHEMBL8182699 | 0.82 | CYP2A6 (0.62) | TOP1TERTCYCSENPP2CYP2A6 | |
| SCHEMBL2423633 | 0.82 | TOP1 (0.76) | TOP1TERTCYCSENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230242-B1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | JOHANNES KEPLER UNI (AT) | 2013-08-14 | — | — | EP | disclosed |
| EP-2230242-A1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | Johannes Kepler Universität (AT) | 2010-09-22 | — | — | EP | disclosed |