SCHEMBL3459753

SCHEMBL3459753

Oc1c(CC2C=CCC2)ccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.49
PKM P14618 1/20 0.49
HIF1A Q16665 1/20 0.49
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749544 0.75 GAA (0.53) GAAPKMHIF1AKDM4EALDH1A1
SCHEMBL27396133 0.73 CYP2D6 (0.47) GAAALDH1A1MAPTKMT2A
SCHEMBL9420976 0.72 GAA (0.53) GAAPKMHIF1AKDM4EALDH1A1
SCHEMBL6758128 0.71 PTPN22 (0.43) GAAPKMHIF1AKDM4EALDH1A1
SCHEMBL6010301 0.69
SCHEMBL29354413 0.69
SCHEMBL130289 0.69 PTPN22 (0.58)
SCHEMBL15345708 0.67 KDM4E (0.55) GAAKDM4EALDH1A1MAPT
SCHEMBL2167788 0.67
SCHEMBL1086963 0.67 PTPN22 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7659051-B2 Polymer having antireflective properties, hardmask composition including the same, and process for forming a patterned material layer CHEIL INDUSTRIES, INC. (KR) 2010-02-09 US disclosed
WO-2008082236-A1 POLYMER HAVING ANTIREFLECTIVE PROPERTIES, HARDMASK COMPOSITION INCLUDING THE SAME, AND PROCESS FOR FORMING A PATTERNED MATERIAL LAYER CHEIL INDUSTRIES INC. (KR) 2008-07-10 WO disclosed
US-20080160460-A1 Polymer having antireflective properties, hardmask composition including the same, and process for forming a patterned material layer CHEIL INDUSTRIES, INC. (KR) 2008-07-03 US disclosed