Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031979 | 0.93 | — | — | |
| SCHEMBL859361 | 0.93 | GCGR (0.33) | GCGR | |
| SCHEMBL7705568 | 0.88 | TOP1 (0.34) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL17442978 | 0.79 | — | — | |
| SCHEMBL1538022 | 0.77 | — | — | |
| SCHEMBL5384591 | 0.76 | CYP3A4 (0.34) | — | |
| SCHEMBL14076169 | 0.72 | — | — | |
| SCHEMBL6036896 | 0.71 | — | — | |
| SCHEMBL8082650 | 0.69 | — | — | |
| SCHEMBL17366427 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230242-B1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | JOHANNES KEPLER UNI (AT) | 2013-08-14 | — | — | EP | disclosed |
| EP-2230242-A1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | Johannes Kepler Universität (AT) | 2010-09-22 | — | — | EP | disclosed |