SCHEMBL3460055

SCHEMBL3460055

[CH2]CCCCCCCCCCC(=C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3461149 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL1455096 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL1454852 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL2122897 1.00
SCHEMBL3462577 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL1453375 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL3461175 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL3462205 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL3463066 1.00 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL3460218 1.00 HSD17B10 (0.33) HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2226632-B1 METHOD FOR SCREENING OF CELL-PROTECTING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-02-12 EP disclosed
US-8450070-B2 Method for screening of cell-protecting agent TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-05-28 US disclosed
US-20100279311-A1 METHOD FOR SCREENING OF CELL-PROTECTING AGENT TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-04 US disclosed
EP-2226632-A1 METHOD FOR SCREENING OF CELL-PROTECTING AGENT Takeda Pharmaceutical Company Limited (JP) 2010-09-08 EP disclosed
US-4631143-A Triphenylene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279311-A1 METHOD FOR SCREENING OF CELL-PROTECTING AGENT HSF1, HSP90AB1, HSP90AA1 HSD17B10 2687/4885TDP1 1790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.