Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
| ▸ | CA4 | P22748 | 4/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851411 | 0.83 | CA1 (0.33) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL3507166 | 0.79 | KDM4E (0.35) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL572568 | 0.78 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL954795 | 0.78 | DPP4 (0.42) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL7817864 | 0.78 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL954895 | 0.78 | DPP4 (0.42) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL18983307 | 0.78 | KDM4E (0.34) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL954793 | 0.78 | DPP4 (0.42) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Water SCHEMBL7151392 | 0.76 | KDM4E (0.37) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL17560337 | 0.76 | DPP4 (0.41) | KDM4EMAPTKMT2AATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872825-B2 | Peptide β-turn mimetic compounds and processes for making them | THE PROCTER & GAMBLE COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| WO-2010043218-A2 | TETRATHIOL LIGANDS, METAL COMPLEXES, CONJUGATES, AND KITS, THE USE THEREOF IN NUCLEAR MEDICINE DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY, AND METHOD FOR PRODUCING THE TETRATHIOL LIGANDS AND METAL COMPLEXES | FORSCHUNGSZENTRUM DRESDEN - ROSSENDORF E. V. (DE) | 2010-04-22 | — | — | WO | disclosed |