⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598 | 1.00 | — | — | |
| SCHEMBL27599 | 1.00 | — | — | |
| SCHEMBL7355661 | 0.79 | — | — | |
| SCHEMBL7355658 | 0.79 | — | — | |
| SCHEMBL7290482 | 0.79 | — | — | |
| SCHEMBL7290489 | 0.79 | — | — | |
| SCHEMBL7355431 | 0.75 | FABP3 (0.45) | — | |
| SCHEMBL7298865 | 0.75 | FABP3 (0.50) | — | |
| SCHEMBL7355429 | 0.75 | FABP3 (0.45) | — | |
| SCHEMBL7298867 | 0.75 | FABP3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023275-A1 | Aqueous Based Pharmaceutical Formulations of 1,2-Dihydropyridine Compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3893844-A1 | AQUEOUS BASED PHARMACEUTICAL FORMULATIONS OF 1,2-DIHYDROPYRIDINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020124090-A1 | AQUEOUS BASED PHARMACEUTICAL FORMULATIONS OF 1,2-DIHYDROPYRIDINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-06-18 | — | — | WO | disclosed |
| EP-1849796-B1 | ANTI-PENICILLIN RESISTANT PNEUMOCOCCI AGENT AND NOVEL 16-MEMBERED RING MACROLIDE DERIVATIVE | MICROBIAL CHEM RES FOUND (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-8507453-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| EP-1614680-B1 | Process for preparing 2-iminopyrrolidine derivatives | EISAI R&D MAN CO LTD (JP) | 2011-12-21 | — | — | EP | disclosed |
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-2385039-A1 | 2-Iminoisoindolinone derivatives as thrombin receptor antagonists | Eisai R&D Management Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-8053418-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-1308441-A1 | 2-AMINOPYRIDINE COMPOUNDS AND USE THEREOF AS DRUGS | Eisai Co., Ltd. (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1300396-A1 | 1,2-DIHYDROPYRIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | Eisai Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |
| EP-1254904-A1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
| EP-1254895-A1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5302711-A | Ester cleavage process for use with β-lactams | ELI LILLY AND COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0557035-A2 | An ester cleavage process for use with beta-lactams | ELI LILLY AND COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0122231-B1 | HERBICIDAL AGENT | CIBA-GEIGY AG (CH) | 1990-01-17 | — | — | EP | disclosed |
| EP-0147365-A2 | Herbicidal agent | CIBA-GEIGY AG (CH) | 1985-07-03 | — | — | EP | disclosed |
| EP-0144283-A1 | Herbicidal agents | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |
| EP-0122231-A2 | Herbicidal agent | CIBA-GEIGY AG (CH) | 1984-10-17 | — | — | EP | disclosed |