⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461857 | 1.00 | — | — | |
| SCHEMBL6967595 | 0.80 | — | — | |
| SCHEMBL216275 | 0.73 | — | — | |
| SCHEMBL216276 | 0.73 | — | — | |
| SCHEMBL11649234 | 0.73 | — | — | |
| SCHEMBL11649238 | 0.73 | — | — | |
| SCHEMBL12806729 | 0.72 | — | — | |
| SCHEMBL11833456 | 0.72 | HSD17B10 (0.30) | — | |
| SCHEMBL21225982 | 0.72 | — | — | |
| SCHEMBL12806728 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437230-B | Tertiary amine compound, diphosphine ligand, intermediate and preparation method thereof | 中国科学院上海有机化学研究所 | 2022-06-21 | — | — | CN | disclosed |
| CN-114560893-A | Planar chiral metallocene compound, and synthesis method and application thereof | 中国科学院上海有机化学研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-110563773-B | Planar chiral ferrocene compound, intermediate thereof, preparation method and application | 中国科学院上海有机化学研究所 | 2022-04-01 | — | — | CN | disclosed |
| CN-110563773-A | Planar chiral ferrocene compound, intermediate thereof, preparation method and application | 中国科学院上海有机化学研究所 | 2019-12-13 | — | — | CN | disclosed |
| EP-2226632-B1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | TAKEDA PHARMACEUTICAL (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8450070-B2 | Method for screening of cell-protecting agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20100279311-A1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2226632-A1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2010-09-08 | — | — | EP | disclosed |