Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24392046 | 0.83 | USP2 (0.41) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL24359182 | 0.83 | NR1H2 (0.43) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL24359183 | 0.81 | USP2 (0.40) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL27221499 | 0.81 | USP2 (0.40) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL22233695 | 0.80 | USP2 (0.41) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL24359199 | 0.78 | HTT (0.38) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL346150 | 0.78 | JAK1 (0.43) | GPR119JAK2JAK1 | |
| SCHEMBL21906695 | 0.76 | USP2 (0.43) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL34473276 | 0.74 | USP2 (0.42) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL345260 | 0.74 | USP2 (0.46) | DDB1CRBNUSP2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216291-B | Carbamate derivatives containing alkyl-heterocycles, preparation and therapeutic use thereof | 赛诺菲-安万特 | 2016-08-03 | — | — | CN | disclosed |
| US-8716289-B2 | Carbamate derivatives of alkyl-heterocycles, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2014-05-06 | — | — | US | disclosed |
| US-20120015950-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2012-01-19 | — | — | US | disclosed |
| CN-102216291-A | Carbamate derivatives containing alkyl-heterocycles, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-10-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015950-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | INTS9, CDK8, SCN8A | DDB1 2959/4885CRBN 646/4885USP2 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.