⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7997982 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL1248 | 0.87 | — | — | |
| Hydroxyamine SCHEMBL15869353 | 0.87 | — | — | |
| Hydroxyamine SCHEMBL3273025 | 0.87 | — | — | |
| Hydroxyamine SCHEMBL23327360 | 0.75 | — | — | |
| Hydroxyamine SCHEMBL482304 | 0.75 | — | — | |
| Hydroxyamine SCHEMBL10610314 | 0.75 | — | — | |
| Hydroxyamine SCHEMBL9773581 | 0.75 | — | — | |
| Hydroxyamine SCHEMBL10496195 | 0.75 | TP53 (0.75) | — | |
| Hydroxyamine SCHEMBL4748440 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079826-A | HDAC inhibitor based on tyrosine skeleton, and synthesis method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-119306697-A | 4-Quinolinone derivative and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | claimed |
| CN-118772156-A | PDE delta/HDAC double-target inhibitor and preparation method and application thereof | 河南师范大学 | 2024-10-15 | — | — | CN | claimed |
| CN-118388409-A | HDAC6/JNK3 double-target anti-Alzheimer disease inhibitor and preparation method and application thereof | 山东大学 | 2024-07-26 | — | — | CN | claimed |
| CN-114539098-B | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2024-05-24 | — | — | CN | claimed |
| CN-115232130-B | APN and AKT double-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-12 | — | — | CN | claimed |
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | claimed |
| CN-116655577-B | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116924959-A | HDAC11 subtype selective inhibitor and preparation method and application thereof | 山东大学 | 2023-10-24 | — | — | CN | claimed |
| CN-115197102-B | Peptide-like hydroxamic acid plasmodium falciparum aminopeptidase inhibitor, and preparation method and application thereof | 山东大学 | 2023-10-20 | — | — | CN | claimed |
| CN-113754591-A | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2021-12-07 | — | — | CN | claimed |
| CN-112500362-A | Oxazole histone deacetylase inhibitor and preparation method thereof | 五邑大学 | 2021-03-16 | — | — | CN | claimed |
| CN-109485074-B | Preparation method of hydroxylamine disulfonic acid potassium and concentration calibration method of hydroxylamine disulfonic acid radical ion | 上海理工大学 | 2020-12-01 | — | — | CN | claimed |
| CN-111635584-A | Preparation method of folding-resistant upper | 扬州爱非科鞋业有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-108299255-B | Histone deacetylase 8 selective inhibitor and preparation method and application thereof | 山东大学 | 2020-05-19 | — | — | CN | claimed |
| CN-111072582-A | N-hydroxy aromatic heterocyclic-2-formamide compound and preparation method and application thereof | 中国药科大学 | 2020-04-28 | — | — | CN | claimed |
| CN-111072586-A | N-hydroxy-3-substituted-5-carboxamide compound and preparation method and application thereof | 中国药科大学 | 2020-04-28 | — | — | CN | claimed |
| CN-108864057-B | JAK and HDAC double-target-point inhibitor containing 4-aminopyrazole structure and preparation method and application thereof | 山东大学 | 2020-03-31 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| US-4668813-A | ION EXCHANGE RESIN | SHOWA SANGYO CO., LTD. (JP) | 1987-05-26 | — | — | US | claimed |