Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ricinoleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.94 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.94 |
| ▸ | FAAH | O00519 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | TERT | O14746 | 3/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | PPARG | P37231 | 3/20 | 0.66 |
| ▸ | PPARD | Q03181 | 3/20 | 0.66 |
| ▸ | PPARA | Q07869 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | FABP4 | P15090 | 2/20 | 0.66 |
| ▸ | F7 | P08709 | 2/20 | 0.66 |
| ▸ | F3 | P13726 | 2/20 | 0.66 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.66 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ricinoleic Acid SCHEMBL28889593 | 1.00 | FFAR1 (0.94) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| Ricinoleic Acid SCHEMBL27493976 | 0.99 | FFAR1 (0.92) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL4979820 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL9401994 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL291095 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23925390 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| Ricinoleic Acid SCHEMBL23532631 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23925391 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL22400911 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| Ricinoleic Acid SCHEMBL25248998 | 0.97 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221197-A1 | ANTIMICROBIAL AGENT AND EXTERNAL PREPARATION FOR SKIN CONTAINING THE SAME | TAIYO CORPORATION (JP) | 2010-09-02 | — | — | US | disclosed |