Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3463669

CCOc1ccc(C(Nc2ccc(C(=N)N)cc2)C(=O)NNC(=O)c2ccccc2)cc1OCC.O=C(O)C(F)(F)F

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F7 P08709 19/20 0.67
F10 P00742 13/20 0.67
PRSS1 P07477 13/20 0.67
F2 P00734 13/20 0.67
F3 P13726 7/20 0.66
PRSS2 P07478 5/20 0.66
PRSS3 P35030 5/20 0.66
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3463466 0.96 F7 (0.63) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3464197 0.95 F7 (0.64) F7F10PRSS1F2F3
SCHEMBL13163000 0.95 F7 (0.74) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL4916194 0.94 F7 (0.68) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3463810 0.93 F7 (0.60) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3464077 0.91 F7 (0.59) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3465447 0.91 F7 (0.60) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3463914 0.90 F7 (0.62) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3464882 0.90 F7 (0.62) F7F10PRSS1F2F3
Trifluoroacetic Acid SCHEMBL3464253 0.90 F7 (0.64) F7F10PRSS1F2F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100240654-A1 HYDRAZIDE DERIVATIVES CLARK RICHARD 2010-09-23 US disclosed
US-20080132507-A1 Hydrazide Derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-06-05 US disclosed
EP-1810965-A1 HYDRAZIDE DERIVATIVES Eisai R&D Management Co., Ltd. (JP) 2007-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240654-A1 HYDRAZIDE DERIVATIVES H1-10, H1-4, H1-3 F7 185/4885F10 11/4885PRSS1 727/4885
US-20080132507-A1 Hydrazide Derivatives H1-10, H1-4, H1-3 F7 185/4885F10 11/4885PRSS1 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.