⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16877485 | 0.96 | — | — | |
| SCHEMBL1037990 | 0.96 | — | — | |
| SCHEMBL17797606 | 0.96 | — | — | |
| SCHEMBL17797570 | 0.96 | — | — | |
| SCHEMBL31167433 | 0.96 | — | — | |
| SCHEMBL31167432 | 0.96 | — | — | |
| SCHEMBL14759743 | 0.93 | — | — | |
| SCHEMBL3464818 | 0.92 | — | — | |
| SCHEMBL14759992 | 0.85 | — | — | |
| SCHEMBL14784477 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070278-A | Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof | 标新生物医药科技(上海)有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-12459958-B2 | Tricyclic compounds as HPK1 inhibitor and the use thereof | BEONE MEDICINES I GMBH (CH) | 2025-11-04 | — | — | US | claimed |
| US-20250248970-A1 | NOVEL SUBSTITUTED FLUORINATED N-PROPYL-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2025-08-07 | — | — | US | claimed |
| US-12252473-B2 | Preparation methods of quinolone compounds and intermediates thereof | Chongqing University of Arts and Sciences (CN) | 2025-03-18 | — | — | US | claimed |
| EP-4508031-A1 | NOVEL SUBSTITUTED FLUORINATED N-PROPYL-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-02-19 | — | — | EP | claimed |
| US-20240400522-A1 | PREPARATION METHODS OF QUINOLONE COMPOUNDS AND INTERMEDIATES THEREOF | Chongqing University of Arts and Sciences (CN) | 2024-12-05 | — | — | US | claimed |
| CN-118984820-A | Novel substituted fluorinated N-propyl-pyrrolidine compounds, methods for the preparation thereof and therapeutic uses thereof | 赛诺菲 | 2024-11-19 | — | — | CN | claimed |
| CN-118834187-A | 6, 6-Difluoro-5-oxygen/azaspiro [2.4] heptane compound and preparation method thereof | 常州大学 | 2024-10-25 | — | — | CN | claimed |
| EP-4448513-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BeiGene Switzerland GmbH (CH) | 2024-10-23 | — | — | EP | claimed |
| CN-118791418-A | Indole compound and preparation method and application thereof | 纽欧申医药(上海)有限公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | claimed |
| WO-2023081840-A1 | KRAS G12C INHIBITORS | FRONTIER MEDICINES CORPORATION (US) | 2023-05-11 | — | — | WO | claimed |
| US-20220267354-A1 | TRICYCLIC COMPOUNDS AS HPK1 INHIBITOR AND THE USE THEREOF | BEONE MEDICINES I GMBH (CH) | 2022-08-25 | — | — | US | claimed |
| CN-113292479-B | Preparation method of 5-azaspiro [2.4] heptane and salt thereof | 南京合巨药业有限公司 | 2022-07-01 | — | — | CN | claimed |
| EP-2842939-B1 | BENZAMIDE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | claimed |
| US-9695118-B2 | Benzamide derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2017-07-04 | — | — | US | claimed |
| US-20160159774-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2016-06-09 | — | — | US | claimed |
| WO-2016090079-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-06-09 | — | — | WO | claimed |
| US-20150152047-A1 | BENZAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-06-04 | — | — | US | claimed |
| EP-2842939-A1 | BENZAMIDE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2015-03-04 | — | — | EP | claimed |