SCHEMBL3463922

SCHEMBL3463922

Cc1[nH]nc(I)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24687302 0.72
SCHEMBL3049122 0.72
SCHEMBL1197102 0.72
SCHEMBL3465152 0.68
SCHEMBL20844009 0.68
SCHEMBL1531052 0.68
SCHEMBL2878037 0.68
SCHEMBL21737572 0.65
SCHEMBL3464222 0.65 HCAR2 (0.42)
SCHEMBL16200189 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11759454-B2 Diazole lactams CHEMOCENTRYX, INC. (US) 2023-09-19 US disclosed
US-20160303084-A1 DIAZOLE LACTAMS CHEMOCENTRYX, INC. 2016-10-20 US disclosed
US-9328116-B2 Diazole lactams CHEMOCENTRYX, INC. (US) 2016-05-03 US disclosed
US-9328116-B2 Diazole lactams CHEMOCENTRYX, INC. (US) 2016-05-03 US disclosed
US-20140171420-A1 DIAZOLE LACTAMS CHEMOCENTRYX, INC. (US) 2014-06-19 US disclosed
US-20140171420-A1 DIAZOLE LACTAMS CHEMOCENTRYX, INC. (US) 2014-06-19 US disclosed
WO-2014089495-A1 DIAZOLE LACTAMS CHEMOCENTRYX, INC. (US) 2014-06-12 WO disclosed
US-8324216-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2012-12-04 US disclosed
US-8324216-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2012-12-04 US disclosed
US-8324216-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2012-12-04 US disclosed
US-20100240618-A1 SUBSTITUTED PIPERAZINES CHEMOCENTRYX, INC. (US) 2010-09-23 US disclosed
CN-100542534-C Substituted piperazines CHEMOCENTRYX INC (US) 2009-09-23 CN disclosed
US-7589199-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2009-09-15 US disclosed
US-7589199-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2009-09-15 US disclosed
US-7589199-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2009-09-15 US disclosed
EP-1691810-A4 SUBSTITUTED PIPERAZINES CHEMOCENTRYX INC (US) 2009-07-01 EP disclosed
EP-1691810-A1 SUBSTITUTED PIPERAZINES ChemoCentryx Inc (US) 2006-08-23 EP disclosed
US-20060106218-A1 Substituted piperazines CHEMOCENTRYX, INC. (US) 2006-05-18 US disclosed
US-20050256130-A1 Substituted piperazines CHEMOCENTRYX, INC. (US) 2005-11-17 US disclosed
WO-2005056015-A1 SUBSTITUTED PIPERAZINES CHEMOCENTRYX, INC. (US) 2005-06-23 WO disclosed