SCHEMBL3465372

SCHEMBL3465372

BrCCCCCCc1cccs1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.57
TSHR P16473 2/20 0.50
NPC1 O15118 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ADRA2A P08913 2/20 0.43
ADRA2B P18089 2/20 0.43
ADRA2C P18825 2/20 0.43
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
RAB9A P51151 3/20 0.39
GLS O94925 1/20 0.38
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091833 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL8104697 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL4841431 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL8100975 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL8105148 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL4847564 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL3609572 1.00 TAAR1 (0.57) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL9670131 0.98 TAAR1 (0.55) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL11461413 0.98 TAAR1 (0.55) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1
SCHEMBL317137 0.98 TAAR1 (0.59) TAAR1TSHRNPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174991-B Fluorescent dye excited and emitted by second window in near infrared region, and preparation method and application thereof 复旦大学 2023-02-10 CN claimed
CN-113659078-A Synaptic transistor device based on novel polyimide gate insulating layer and preparation method thereof 南开大学 2021-11-16 CN claimed
CN-112174991-B Fluorescent dye excited and emitted by second window in near infrared region, and preparation method and application thereof 复旦大学 2023-02-10 CN disclosed
CN-114122260-A PIN heterojunction based artificial synapse at two ends and preparation method thereof 南开大学 2022-03-01 CN disclosed
CN-113659078-A Synaptic transistor device based on novel polyimide gate insulating layer and preparation method thereof 南开大学 2021-11-16 CN disclosed
CN-112174991-A Fluorescent dye excited and emitted by second window in near infrared region, and preparation method and application thereof 复旦大学 2021-01-05 CN disclosed
EP-2148747-B1 THIN FILMS OF CONJUGATED POLYMERS CONTAINING INORGANIC NANOPARTICLES AND MANUFACTURING PROCESS THEREOF COMMISSARIAT ENERGIE ATOMIQUE (FR) 2018-11-28 EP disclosed
US-8440258-B2 Thin films of conjugated polymers containing inorganic nanoparticles and process for the manufacture thereof COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2013-05-14 US disclosed
CN-101775123-B Polyfluorene conjugated polymer with thiophene and other aromatic heterocycles on C9 side chain, and preparation method and application thereof UNIV SOUTH CHINA NORMAL 2012-05-23 CN disclosed
US-20100183855-A1 THIN FILMS OF CONJUGATED POLYMERS CONTAINING INORGANIC NANOPARTICLES AND PROCESS FOR THE MANUFACTURE THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-07-22 US disclosed
CN-101775123-A Polyfluorene conjugated polymer with thiophene and other aromatic heterocycle at C9 side chain, and preparation method and applications thereof UNIV SOUTH CHINA NORMAL 2010-07-14 CN disclosed
EP-2148747-A2 THIN FILMS OF CONJUGATED POLYMERS CONTAINING INORGANIC NANOPARTICLES AND MANUFACTURING PROCESS THEREOF Commissariat à l'Energie Atomique (FR) 2010-02-03 EP disclosed
WO-2008152295-A2 THIN FILMS OF CONJUGATED POLYMERS CONTAINING INORGANIC NANOPARTICLES AND PROCESS FOR THE MANUFACTURE THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-12-18 WO disclosed
US-6166003-A Heterocyclic compounds for cancer chemoprevention LKT LABORATORIES, INC. (US) 2000-12-26 US disclosed
WO-2000049013-A1 ISOTHIO CYANATO ALKYLTHIOPHENES AS CANCER CHEMOPROTECTIVE AGENTS LKT LABORATORIES, INC. (US) 2000-08-24 WO disclosed
EP-1025145-A1 MEANS AND METHODS FOR ENHANCING INTERFACIAL ADHESION BETWEEN A METAL SURFACE AND A NON-METALLIC MEDIUM AND PRODUCTS OBTAINED THEREBY N.V. BEKAERT S.A. (BE) 2000-08-09 EP disclosed
WO-1999020682-A1 MEANS AND METHODS FOR ENHANCING INTERFACIAL ADHESION BETWEEN A METAL SURFACE AND A NON-METALLIC MEDIUM AND PRODUCTS OBTAINED THEREBY N.V. BEKAERT S.A. (BE) 1999-04-29 WO disclosed
EP-0275024-B1 CARBOXYLIC-ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1991-09-04 EP disclosed
US-4833161-A ANTIDIABETIC AGENTS, ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1989-05-23 US disclosed
EP-0275024-A1 Carboxylic-acid derivatives, processes for their preparation and medicaments containing these compounds Roche Diagnostics GmbH (DE) 1988-07-20 EP disclosed