Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 19/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | CDC37 | Q16543 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465524 | 0.82 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL3465149 | 0.82 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1 | |
| SCHEMBL3464479 | 0.80 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CDC37HSP90B1 | |
| SCHEMBL3464959 | 0.79 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1CDC37HSP90B1 | |
| SCHEMBL3464443 | 0.79 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1CDC37HSP90B1 | |
| SCHEMBL3464855 | 0.77 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL3465807 | 0.72 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL3466170 | 0.72 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL3465516 | 0.70 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL3464776 | 0.69 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1CDC37HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2010-09-23 | — | — | US | claimed |
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | HSP90AA1 3/4885HSP90AB1 1/4885CDC37 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.