Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938535 | 0.84 | HCRTR1 (0.50) | HCRTR1HCRTR2SCDPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL224268 | 0.83 | HCRTR1 (0.49) | HCRTR1HCRTR2SCDPSEN1PSEN2 | |
| SCHEMBL2821695 | 0.76 | HCRTR1 (0.50) | HCRTR1HCRTR2SCDP2RX7PSEN1 | |
| SCHEMBL2820773 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2SCDP2RX7PSEN1 | |
| SCHEMBL2825405 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2SCDP2RX7PSEN1 | |
| SCHEMBL2817774 | 0.73 | HCRTR1 (0.48) | HCRTR1HCRTR2SCDP2RX7MGLL | |
| SCHEMBL30691929 | 0.73 | GPR183 (0.50) | HCRTR1HCRTR2SCDP2RX7GPR183 | |
| SCHEMBL937498 | 0.73 | GPR183 (0.50) | HCRTR1HCRTR2SCDP2RX7GPR183 | |
| SCHEMBL1222670 | 0.73 | SCD (0.48) | HCRTR1HCRTR2SCDP2RX7PSEN1 | |
| Hydrochloric Acid SCHEMBL2817771 | 0.72 | HCRTR1 (0.48) | HCRTR1HCRTR2SCDP2RX7MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075356-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-01 | — | — | WO | disclosed |