Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467238 | 1.00 | MEN1 (0.72) | MEN1KMT2ASIRT2SIRT1TTR | |
| SCHEMBL3467236 | 1.00 | MEN1 (0.72) | MEN1KMT2ASIRT2SIRT1TTR | |
| SCHEMBL11907672 | 0.85 | SIRT2 (0.77) | MEN1KMT2ASIRT2SIRT1TTR | |
| SCHEMBL10749176 | 0.76 | MEN1 (0.57) | MEN1KMT2AGSK3BGAAPOLB | |
| SCHEMBL11134601 | 0.76 | GSK3B (0.54) | MEN1KMT2AGSK3BPIM1GAA | |
| SCHEMBL7690119 | 0.76 | GAA (0.59) | MEN1KMT2ATTRGSK3BGAA | |
| SCHEMBL8219412 | 0.76 | MAPT (0.53) | MEN1KMT2AGSK3BGAAPOLB | |
| SCHEMBL10749179 | 0.76 | MEN1 (0.57) | MEN1KMT2AGSK3BGAAPOLB | |
| SCHEMBL15421542 | 0.76 | MEN1 (0.57) | MEN1KMT2AGSK3BGAAPOLB | |
| SCHEMBL7690121 | 0.76 | GAA (0.59) | MEN1KMT2ATTRGSK3BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-0695749-B1 | Process for the selective hydrogenation of activated, ethylenically unsaturated compounds | RUETGERS ORGANICS GMBH (DE) | 1998-11-25 | — | — | EP | disclosed |
| EP-0695749-A1 | Process for the selective hydrogenation of activated, ethylenically unsaturated compounds | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |