Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 14/20 | 0.69 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467508 | 1.00 | HRH4 (0.69) | HRH4NUDT1ROCK1CHRM3PDE4A | |
| SCHEMBL18601605 | 0.97 | HRH4 (0.67) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL18636736 | 0.85 | HRH4 (0.67) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL12605022 | 0.85 | HRH4 (0.67) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL1775550 | 0.84 | HRH4 (0.66) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL1775551 | 0.84 | HRH4 (0.66) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL3190045 | 0.84 | HRH4 (0.60) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL3190040 | 0.84 | HRH4 (0.60) | HRH4NUDT1ROCK1HTR3A | |
| SCHEMBL18486240 | 0.81 | HRH4 (0.62) | HRH4ROCK1HTR3A | |
| SCHEMBL5155514 | 0.81 | HRH4 (0.62) | HRH4ROCK1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072829-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-07-01 | — | — | WO | disclosed |