Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971402 | 1.00 | GAA (0.51) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL18933078 | 0.91 | GAA (0.44) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL702046 | 0.89 | GAA (0.59) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL655620 | 0.89 | GAA (0.59) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL655621 | 0.89 | GAA (0.59) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL14275809 | 0.89 | PDE4B (0.42) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL4987475 | 0.86 | GAA (0.60) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL1404236 | 0.86 | POLB (0.50) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL31554318 | 0.86 | POLB (0.50) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL31554325 | 0.86 | POLB (0.50) | GAAALDH1A1THRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072823-A1 | PYRAZOLE[1,5a]PYRIDINE DERIVATIVES | PALAU PHARMA, S. A. (ES) | 2010-07-01 | — | — | WO | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-4005208-A | GASTRIC JUICE, ANTISECRETORY | SMITHKLINE CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |