⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830181 | 0.55 | — | — | |
| SCHEMBL1381999 | 0.46 | — | — | |
| SCHEMBL27946454 | 0.36 | — | — | |
| SCHEMBL11781196 | 0.35 | — | — | |
| Hydrogen Sulfide SCHEMBL313917 | 0.32 | — | — | |
| SCHEMBL14698201 | 0.32 | — | — | |
| SCHEMBL1225965 | 0.30 | — | — | |
| SCHEMBL7507 | 0.30 | — | — | |
| SCHEMBL28637376 | 0.30 | CA1 (1.00) | — | |
| SCHEMBL4070125 | 0.30 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328619-B1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | Baxalta GmbH (CH) | 2016-12-07 | — | — | EP | claimed |
| US-20150057221-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | ASCENDIS PHARMA AS (DK) | 2015-02-26 | — | — | US | claimed |
| US-8906847-B2 | Prodrug comprising a drug linker conjugate | ASCENDIS PHARMA A/S (DK) | 2014-12-09 | — | — | US | claimed |
| US-8653131-B2 | Polymeric benzyl carbonate-derivatives | BAXTER HEALTHCARE S.A. (CH) | 2014-02-18 | — | — | US | claimed |
| JP-2012500804-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2328619-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | Baxter International Inc. (US) | 2011-06-08 | — | — | EP | claimed |
| JP-2011510954-A | — | — | 2011-04-07 | — | — | JP | claimed |
| US-20110053848-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | ASCENDIS PHARMA AS (DK) | 2011-03-03 | — | — | US | claimed |
| EP-2237799-A2 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | Ascendis Pharma AS (DK) | 2010-10-13 | — | — | EP | claimed |
| US-20100048483-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER HEALTHCARE S.A. (CH) | 2010-02-25 | — | — | US | claimed |
| WO-1994025488-A1 | METHOD FOR PREPARING A METAL-RADIONUCLIDE-LABELLED PROTEIN | MALLINCKRODT MEDICAL, INC. (US) | 1994-11-10 | — | — | WO | claimed |
| EP-0239853-B1 | 3,4-DISUBSTITUTED-2-AZETIDINONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| US-5162307-A | Treatment of emphysema | BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) | 1992-11-10 | — | — | US | claimed |
| US-5075437-A | 3,4-DISUBSTITUTED-2-AZETIDINONE DERIVATIVES AND PROCESSES FOR PREPARATION USING TIN ENOLATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | claimed |
| EP-0403605-A4 | ELASTASE INHIBITING POLYMERS AND METHODS | UNIV KENTUCKY RES FOUND (US) | 1991-08-21 | — | — | EP | claimed |
| EP-0403605-A1 | ELASTASE INHIBITING POLYMERS AND METHODS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-12-27 | — | — | EP | claimed |
| EP-0368449-A2 | Elastase inhibiting polymers and methods to produce them | Digenis, George Alexander (US) | 1990-05-16 | — | — | EP | claimed |
| WO-1990002558-A1 | ELASTASE INHIBITING POLYMERS AND METHODS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-03-22 | — | — | WO | claimed |
| EP-0239853-A1 | 3,4-Disubstituted-2-azetidinone derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | claimed |
| US-4643991-A | TREATMENT OF EMPHYSEMA | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1987-02-17 | — | — | US | claimed |