SCHEMBL3468136

SCHEMBL3468136

CC(=O)O[C@H](C=O)[C@@H](OCc1ccccc1)[C@H](OCc1ccccc1)[C@H](O)COCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
SLC1A1 P43005 3/20 0.37
SLC1A3 P43003 2/20 0.37
SLC1A2 P43004 2/20 0.37
CYP2C19 P33261 2/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
TACR1 P25103 1/20 0.37
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1578765 1.00 KMT2A (0.41) KMT2AALDH1A1CA1CA2CA7
Diphenylsulfane SCHEMBL4401424 0.94 KMT2A (0.37) KMT2AALDH1A1CA1CA2CA7
SCHEMBL1674203 0.87 CA1 (0.44) KMT2ACA1CA2CA7CA9
SCHEMBL1479599 0.87 CA1 (0.44) KMT2ACA1CA2CA7CA9
SCHEMBL2290678 0.87 CA1 (0.44) KMT2ACA1CA2CA7CA9
SCHEMBL23292518 0.87 CA1 (0.44) KMT2ACA1CA2CA7CA9
SCHEMBL1561831 0.83 CA1 (0.45) KMT2ACA1CA2CA7CA9
SCHEMBL2562479 0.83 CA1 (0.45) KMT2ACA1CA2CA7CA9
SCHEMBL3751041 0.83 CA1 (0.45) KMT2ACA1CA2CA7CA9
SCHEMBL1263178 0.83 CA1 (0.45) KMT2ACA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212541-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES AND THEIR INTERMEDIATES Genzyme Corporation (US) 2023-07-19 EP disclosed
US-20220242899-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2022-08-04 US disclosed
US-11279725-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2022-03-22 US disclosed
US-20200216485-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2020-07-09 US disclosed
EP-3608330-A2 SYNTHETIC INTERMEDIATES FOR PREPARING OLIGOSACCHARIDE-PROTEIN CONJUGATES Genzyme Corporation (US) 2020-02-12 EP disclosed
US-10464962-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2019-11-05 US disclosed
EP-2889043-B1 Synthetic intermediates for preparing oligosaccharide-protein conjugates GENZYME CORP (US) 2019-04-10 EP disclosed
US-20180002365-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2018-01-04 US disclosed
US-9493498-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2016-11-15 US disclosed
EP-2889043-A2 Oligosaccharide-protein conjugates Genzyme Corporation (US) 2015-07-01 EP disclosed
US-20150175643-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2015-06-25 US disclosed
EP-2465542-B1 Oligosaccharide-protein conjugates GENZYME CORP (US) 2015-01-21 EP disclosed
US-8835614-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2014-09-16 US disclosed
EP-2465542-A1 Oligosaccharide-protein conjugates Genzyme Corporation (US) 2012-06-20 EP disclosed
US-20110300120-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2011-12-08 US disclosed
WO-2010075010-A2 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION (US) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242899-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885
US-20200216485-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885
US-20110300120-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885
US-20150175643-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885
US-10464962-B2 Oligosaccharide-protein conjugates MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885
US-11279725-B2 Oligosaccharide-protein conjugates MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885
US-20180002365-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 KMT2A 3781/4885ALDH1A1 2313/4885CA1 3117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.