SCHEMBL3468515

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3468209	0.92	ESR1 (0.42)	CYP19A1ESR1ESR2NR1I2LTA4H
	SCHEMBL3081636	0.89	GAA (0.52)	CYP19A1ESR1ESR2NR1I2GAA
	SCHEMBL3082749	0.88	NR1I2 (0.43)	CYP19A1ESR1ESR2NR1I2GAA
	SCHEMBL4729921	0.86	ESR1 (0.51)	ESR1ESR2CYP3A4ESRRGALDH1A1
	Hydrochloric Acid SCHEMBL4728833	0.85	ESR1 (0.50)	ESR1ESR2CYP3A4ESRRGALDH1A1
	SCHEMBL3469364	0.84	ESR1 (0.47)	ESR1ESR2GAA
	SCHEMBL3468408	0.82	ESR1 (0.56)	ESR1ESR2NR1I2GAACYP1A2
	SCHEMBL3081328	0.82	GAA (0.45)	CYP19A1ESR1ESR2NR1I2GAA
	SCHEMBL13161273	0.82	ESR1 (0.41)	CYP19A1ESR1ESR2LTA4HNR5A1
	SCHEMBL3073731	0.82	GAA (0.43)	CYP19A1ESR1ESR2GAAESRRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.