SCHEMBL3468538

SCHEMBL3468538

Oc1c(O)c(Cl)c(Cl)c(Cl)c1Cl.[Co]

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.75
TSHR P16473 7/20 0.75
HPGD P15428 7/20 0.75
ALDH1A1 P00352 3/20 0.75
MEN1 O00255 2/20 0.75
LMNA P02545 2/20 0.75
MAPT P10636 2/20 0.75
KMT2A Q03164 2/20 0.75
CYP1A2 P05177 4/20 0.43
CYP2C9 P11712 4/20 0.43
HIF1A Q16665 3/20 0.43
MAPK1 P28482 3/20 0.42
CYP3A4 P08684 5/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
BRCA1 P38398 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68786 0.95 HSD17B10 (0.82) HSD17B10TSHRHPGDALDH1A1MEN1
Water SCHEMBL8652184 0.91 HPGD (0.75) HSD17B10TSHRHPGDALDH1A1MEN1
SCHEMBL21409526 0.91 HSD17B10 (0.75) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL5315995 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL1330735 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL23121452 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Perchlorobenzene SCHEMBL28269084 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL1492 0.86 HSD17B10 (1.00) HSD17B10TSHRHPGDALDH1A1MEN1
Boric Acid SCHEMBL27587380 0.84 TSHR (0.64) HSD17B10TSHRHPGDALDH1A1MEN1
Pentachlorophenol SCHEMBL21647360 0.82 HSD17B10 (0.91) HSD17B10TSHRHPGDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7855311-B2 Formation of hydroxycarbonyl compounds CARTER MELVIN K 2010-12-21 US claimed
US-20100234644-A1 Formation of hydroxycarbonl compounds CARTER TECHNOLOGIES (US) 2010-09-16 US claimed
US-20090112026-A1 Formation of hydroxycarbonyl compounds CARTER TECHNOLOGIES (US) 2009-04-30 US claimed