SCHEMBL3468554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3468408	0.88	ESR1 (0.56)	ESR1FYNESR2CA1CA2
	Gsk-232802 SCHEMBL3467757	0.86	ESR1 (0.55)	ESR1CA1CA2TSHRKMT2A
	SCHEMBL3468569	0.86	ESR1 (0.59)	ESR1ESR2CA1CA2MAPT
	SCHEMBL3468462	0.85	ESR1 (0.43)	ESR1FYNPARP1HPGDKMT2A
	SCHEMBL3468530	0.82	ESR1 (0.54)	ESR1ESR2MAPTLMNAKMT2A
	SCHEMBL3468528	0.82	ESR1 (0.54)	ESR1ESR2MAPTLMNAKMT2A
	SCHEMBL3075044	0.82	ESR1 (0.50)	ESR1ESR2CA1CA2MAPT
	SCHEMBL3468080	0.82	ESR1 (0.51)	ESR1CA1CA2MAPTLMNA
	SCHEMBL3467621	0.82	CA1 (0.59)	ESR1ESR2CA1CA2TSHR
	SCHEMBL3468485	0.81	ESR1 (0.49)	ESR1ESR2MAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.