Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82511 | 1.00 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87855 | 0.93 | GSK3B (0.64) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87886 | 0.93 | GSK3B (0.64) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL83720 | 0.92 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL83029 | 0.92 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL83055 | 0.92 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87869 | 0.92 | GSK3B (0.64) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87870 | 0.90 | GSK3B (0.60) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87918 | 0.90 | GSK3B (0.60) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87728 | 0.90 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261224-A2 | 6-(Pyridinyl)-4-pyrimidone derivatives as tau protein kinase 1 inhibitors | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |