SCHEMBL346928

SCHEMBL346928

C=C(C)C(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDE4A P27815 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
THRB P10828 1/20 0.39
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193930 1.00 TSHR (0.55) TSHRLMNAL3MBTL1PDE4ATDP1
SCHEMBL306870 1.00 TSHR (0.55) TSHRLMNAL3MBTL1PDE4ATDP1
SCHEMBL1426922 0.96 TSHR (0.55) TSHRLMNAL3MBTL1PDE4ATDP1
SCHEMBL306496 0.96 TSHR (0.55) TSHRLMNAL3MBTL1PDE4ATDP1
SCHEMBL15903494 0.95 TSHR (0.50) TSHRLMNAL3MBTL1PDE4ATDP1
SCHEMBL2845656 0.92 TSHR (0.63) TSHRTDP1THRBALDH1A1
SCHEMBL5827538 0.89 TSHR (0.59) TSHRTDP1THRBALDH1A1
SCHEMBL346926 0.89 TSHR (0.59) TSHRTDP1THRBALDH1A1
SCHEMBL4268354 0.89 TSHR (0.59) TSHRTDP1THRBALDH1A1
SCHEMBL2845172 0.88 TSHR (0.63) TSHRTDP1THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749960-B Polycarboxylic acid super-plasticizer and its preparation method and application with diesis core configuration 中科院广州化学有限公司南雄材料生产基地 2019-07-02 CN claimed
CN-106749960-A Polycarboxylic acid super-plasticizer and its preparation method and application with diesis core configuration 中科院广州化学有限公司南雄材料生产基地 2017-05-31 CN claimed
US-20090294362-A1 STATIONARY PHASE FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2009-12-03 US claimed
EP-4097155-B1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF CLEARLAB SG PTE LTD (SG) 2025-08-20 EP disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-12024597-B2 Wound dressings comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-02 US disclosed
EP-4378967-A1 (METH)ACRYLAMIDE COMPOUND, MONOMER COMPOSITION, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2024-06-05 EP disclosed
US-20240165588-A1 METHOD FOR PRODUCING CARRIER FOR CHROMATOGRAPHIC USE, METHOD FOR PRODUCING CHROMATOGRAPHY COLUMN, AND CARRIER FOR CHROMATOGRAPHIC USE JSR CORPORATION (JP) 2024-05-23 US disclosed
WO-2024096019-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-05-10 WO disclosed
EP-4360609-A1 DENTAL ADHESIVE KIT Kuraray Noritake Dental Inc. (JP) 2024-05-01 EP disclosed
US-20240116027-A1 METHOD FOR PRODUCING CHROMATOGRAPHY CARRIER, METHOD FOR PRODUCING CHROMATOGRAPHY COLUMN, AND CHROMATOGRAPHY CARRIER JSR CORPORATION (JP) 2024-04-11 US disclosed
EP-2562178-B1 FILLER FOR AFFINITY CHROMATOGRAPHY JSR CORP (JP) 2015-05-06 EP disclosed
EP-2656831-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2013-10-30 EP disclosed
US-20130274426-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2013-10-17 US disclosed
US-8545225-B2 Redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2013-10-01 US disclosed
EP-2562178-A1 FILLER FOR AFFINITY CHROMATOGRAPHY JSR Corporation (JP) 2013-02-27 EP disclosed
US-20130023650-A1 FILLER FOR AFFINITY CHROMATOGRAPHY JSR CORPORATION (JP) 2013-01-24 US disclosed
EP-2409997-A1 REDOX-CURING TYPE COMPOSITION Kuraray Medical Inc. (JP) 2012-01-25 EP disclosed
US-20120016094-A1 REDOX-CURING TYPE COMPOSITION KURARAY MEDICAL INC. (JP) 2012-01-19 US disclosed
US-20090294362-A1 STATIONARY PHASE FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130274426-A1 DENTAL CURABLE COMPOSITION BAZ2B, BRPF3, SHH TSHR 3521/4885LMNA 4208/4885L3MBTL1 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.