Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306126 | 0.87 | NPSR1 (0.47) | NPSR1LMNAMAPTCNR2KDM4E | |
| SCHEMBL338481 | 0.87 | NPSR1 (0.47) | NPSR1LMNAMAPTCNR2SMN1; SMN2 | |
| SCHEMBL12306125 | 0.80 | NPSR1 (0.41) | NPSR1LMNAMAPTCNR2FPR1 | |
| SCHEMBL341063 | 0.80 | NPSR1 (0.46) | NPSR1LMNAMAPTCNR2SMN1; SMN2 | |
| SCHEMBL12306124 | 0.79 | NPSR1 (0.41) | NPSR1LMNAMAPTCNR2SMN1; SMN2 | |
| SCHEMBL12359024 | 0.79 | NPSR1 (0.41) | NPSR1LMNAMAPTCNR2SMN1; SMN2 | |
| SCHEMBL345692 | 0.79 | NPSR1 (0.40) | NPSR1LMNAMAPTCNR2FPR1 | |
| SCHEMBL12359164 | 0.78 | NPSR1 (0.39) | NPSR1LMNAMAPTCNR2FPR1 | |
| SCHEMBL344043 | 0.78 | NPSR1 (0.49) | NPSR1LMNAMAPTCNR2SMN1; SMN2 | |
| SCHEMBL12318935 | 0.75 | NPSR1 (0.37) | NPSR1LMNAMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321319-B1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-03-14 | — | — | EP | disclosed |