Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017295 | 0.95 | TSHR (0.56) | TSHRALDH1A1TP53 | |
| Alcohol SCHEMBL462789 | 0.87 | — | — | |
| SCHEMBL28079703 | 0.84 | — | — | |
| Alcohol SCHEMBL472182 | 0.84 | — | — | |
| SCHEMBL11115306 | 0.81 | TSHR (0.67) | TSHRALDH1A1TP53 | |
| SCHEMBL1883305 | 0.79 | TSHR (0.67) | TSHRALDH1A1TP53 | |
| Propanol SCHEMBL29120875 | 0.78 | — | — | |
| Ethylene Glycol SCHEMBL35862 | 0.78 | — | — | |
| SCHEMBL11589496 | 0.78 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL1836 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266927-B1 | Polymer for ultra-high strength concrete admixture and method for preparing the same | SILKROAD C & T CO LTD (KR) | 2013-10-02 | — | — | EP | disclosed |
| EP-2266927-A1 | Polymer for ultra-high strength concrete admixture and method for preparing the same | Silkroad C&T Co., LTD (KR) | 2010-12-29 | — | — | EP | disclosed |