SCHEMBL3471123

SCHEMBL3471123

NS(=O)(=O)C(=O)S(N)(=O)=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
CA5A P35218 3/20 0.46
CA5B Q9Y2D0 3/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA7 P43166 2/20 0.46
TSHR P16473 1/20 0.46
NT5E P21589 1/20 0.46
CA12 O43570 1/20 0.38
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10473101 0.96 CA1 (0.43) CA1CA2CA9CA5ACA5B
SCHEMBL5315226 0.73
SCHEMBL2772640 0.73
SCHEMBL5155872 0.70
SCHEMBL28178943 0.70
SCHEMBL467288 0.70
Hydrochloric Acid SCHEMBL5155881 0.70
SCHEMBL31508509 0.67
SCHEMBL27673478 0.67
SCHEMBL29088734 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1111453-A Aryl sulfonamide derivatives and pharmaceutical compositions containing the same NIPPON KOKAN KK (JP) 1995-11-08 CN claimed
JP-9327972-A None JP disclosed
US-12571023-B2 Composition and methods for affinity directed enrichment of rare species SPARK MOLECULAR DIAGNOSTICS, INC. (US) 2026-03-10 US disclosed
CN-115417852-B 5-trifluoromethyl-4H-thiopyran derivatives and process for preparing same 华东师范大学 2023-12-01 CN disclosed
WO-2023119910-A1 RADIATION-SENSITIVE COMPOSITION, RESIST PATTERN FORMATION METHOD, ACID GENERATOR, AND COMPOUND JSR株式会社 2023-06-29 WO disclosed
CN-114181530-A Bioelectrode composition, bioelectrode, method for producing bioelectrode, and silicon material particle 信越化学工业株式会社 2022-03-15 CN disclosed
CN-112400026-A Compositions and methods for affinity directed enrichment of rare species CY分子诊断公司 2021-02-23 CN disclosed
US-20150259295-A1 SUBSTITUTED PYRAZOLE COMPOUNDS AS LPAR ANTAGONISTS HOFFMANN-LA ROCHE INC. 2015-09-17 US disclosed
EP-2864294-A1 SUBSTITUTED PYRAZOLE COMPOUNDS AS LPAR ANTAGONISTS F. Hoffmann-La Roche AG (CH) 2015-04-29 EP disclosed
WO-2013189862-A1 SUBSTITUTED PYRAZOLE COMPOUNDS AS LPAR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2013-12-27 WO disclosed
US-5877199-A ALZHEIMER'S DISEASE; SEDATIVE SANKYO COMPANY, LIMITED (JP) 1999-03-02 US disclosed
WO-1999005125-A1 SUBSTITUTED N-ARYL-N-THIOXOCARBONYL SULFONAMIDES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-02-04 WO disclosed
JP-H09327972-A THERMAL RECORDING MATERIAL NIPPON PAPER IND CO LTD 1997-12-22 JP disclosed
US-5607954-A Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-04 US disclosed
CN-1111453-A Aryl sulfonamide derivatives and pharmaceutical compositions containing the same NIPPON KOKAN KK (JP) 1995-11-08 CN disclosed
US-4908056-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-13 US disclosed
US-4908056-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-13 US disclosed
US-4838925-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-06-13 US disclosed
US-4838925-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-06-13 US disclosed
EP-0244166-A2 Heterocyclic acetyl sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571023-B2 Composition and methods for affinity directed enrichment of rare species CPSF6, CPSF1, NUDT21 CA1 955/4885CA2 1956/4885CA9 1462/4885
US-20150259295-A1 SUBSTITUTED PYRAZOLE COMPOUNDS AS LPAR ANTAGONISTS LPAR3, LPAR1, LPAR2 CA1 4864/4885CA2 4168/4885CA9 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.